Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic

Accurate assessment of the Boyle temperature of nonpolar molecular gases using second virial coefficient with Lennard-Jones (12-6) potential

WOS: 000467484800002We derived an efficient analytical formula to calculate the second virial coefficient in the Lennard-Jones (12-6) potential. The analytical formula is used to accurately evaluate the Boyle temperature. The Boyle temperature is determined for nonpolar molecules from the second virial coefficient, and the calculated results are compared with other studies. The accuracies of the second virial coefficient and the Boyle temperature are tested by their application to molecules Kr,Xe,Ne,Ar,He,H2,O2,F2,Cl2,I2,Br2,SF6,SO3,CH4,C2H6,C3H6,C5H10,C4H6,CO2,ClFO3,CCl4,SiH4, The obtained results for the second virial coefficient at a wide temperature range and the Boyle temperature are in good agreement with the known data available in the literature.Scientific and Technological Research Council of Turkey (TUBITAK) Science Fellowships and Grant Programmes Department (BIDEB)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)This work has been supported by the Scientific and Technological Research Council of Turkey (TUBITAK) Science Fellowships and Grant Programmes Department (BIDEB)

Evaluation of Quantum Corrections to Second Virial Coefficient with Lennard-Jones (12-6) Potential

International Conference on Quantum Science and Applications (ICQSA) -- MAY 25-27, 2016 -- Eskisehir Osmangazi University, Eskisehir, TURKEYWOS: 000440515300010The efficient method is developed for analytical evalualtion of quantum corrections to second virial coefficient with Lennard-Jones (12-6) potential. The quantum corrections to second virial coefficient played a significant role in the investigation of real gases in the low temperatures range. In this paper, we obtained a series of formula in terms of gamma and exponential integral functions which is one of the useful approaches for analytical evaluation of quantum corrections to second virial coefficient. The calculation results excellently agreement with of the literature data.Eskisehir Osmangazi Univ, Ctr Quantum Res & Applications, Eskisehir Osmangazi Univ (ESOGU

Analytical evaluation of zero-pressure Joule-Thomson coefficient using second virial coefficient and its application

WOS: 000392514900015In this paper, we present an analytical procedure to evaluate the zero-pressure Joule-Thomson coefficient using the second virial coefficient over the Lennard-Jones (12-6) potential. The analytical expressions are derived for the first and second derivatives of the second virial coefficient. The proposed formulae guarantee the accurate and fast calculation of the Joule-Thomson coefficient. As an example of application, the analytical expression obtained is used to calculate results for the molecules He, Xe, , , , , , and . The results obtained by the present analytical expression are found to be in good agreement with the data in the literature. The calculation of results will help to estimate the Joule-Thomson coefficient with sufficient reliability and to determine the interaction potentials

Analytical treatment of second virial coefficient over Lennard-Jones (2n-n) potential and its application to molecular systems (vol 1068, pg 164, 2014)

WOS: 000401593400067

Unified analytical formulae of second virial coefficient with kihara potential and its application to real gases

We propose a general evaluation method to calculate the second virial coefficient with Kihara potential (spherical core). The suggested approach is based on exponential function series expansion formula and gamma functions, which enable us to have accurate evaluation of the second virial coefficient. The results of second virial coefficient determined from Kihara potential are compared with the calculations of second virial coefficient with Lennard- Jones (12-6) potential. The analytical formula allows an accurate determination of Boyle temperature of gases. The accuracy of the obtained formula is tested by its application to gases Ar, Kr, Ne, CH4, C6H6, C3H8, n-C4H10, and n-C5H12. The results of the second virial coefficient in a wide temperature range and Boyle temperature are in good agreement with the data available in the literature. © 2020 Polish Academy of Sciences. All rights reserved

Intestinal duplication cyst associated with intestinal malrotation anomaly: Report of a case

WOS: 000242091700029PubMed: 17168282Duplications of the alimentary tract are rare congenital malformations and may occur anywhere in the intestinal tract. Intestinal duplication cysts have been rarely found with intestinal malrotation anomaly. We present a 2-year old boy who had intestinal duplication cyst, associated with intestinal malrotation anomaly

Autorevascularization of the testicle and spermatic vessels by Madder pedicle flap: an experimental study

WOS: 000231729200015PubMed: 16080935Purpose: The aim of the study was to investigate revascularization of the testicle through its own tissue and spermatic vessels by a bladder pedicle flap in rabbits. Methods: Thirty male rabbits were used in the study. In 10 animals, the Fowler-Stephens (FS) procedure was applied to the right testicles (FS group). The FS procedure and revascularization of the testicle by a bladder pedicle flap were applied to the right testicles in 10 animals (FSO group). No surgical procedure was performed in the control group. Scintigraphic study was performed 3 weeks after the high ligation procedure in the FS and FSO groups. Both testicles were evaluated by radionuclide scintigraphy in all the animals. Macroscopic testicle weights were evaluated. Testicular biopsy scores and mean seminiferous tubule diameters were determined in the histopathologic study. Results: The testicular blood flow of the FSO group was better than the FS group (P .01). Testicle weights, testicular biopsy scores, and seminiferous tubule diameters ill the FSO group were detected, and there was a statistically significant difference when compared with the FS group (P .01). Conclusion: We suppose that the surgical model of revascularization of the testicle through its own tissue and spermatic vessels by a bladder pedicle flap can be an alternative to the FS procedure in abdominal and high canalicular undescended testicles. (c) 2005 Elsevier Inc. All rights reserved